International Science Index


1502

The Integrated Studies of Infectious Disease Using Mathematical Modeling and Computer Simulation

Abstract:In this paper we develop and analyze the model for the spread of Leptospirosis by age group in Thailand, between 1997 and 2010 by using mathematical modeling and computer simulation. Leptospirosis is caused by pathogenic spirochetes of the genus Leptospira. It is a zoonotic disease of global importance and an emerging health problem in Thailand. In Thailand, leptospirosis is a reportable disease, the top three age groups are 23.31% in 35-44 years olds group, 22.76% in 25-34 year olds group, 17.60% in 45-54 year olds group from reported leptospirosis between 1997 and 2010, with a peak in 35-44 year olds group. Our paper, the Leptosipirosis transmission by age group in Thailand is studied on the mathematical model. Some analytical and simulation results are presented.
References:
[1] A. R. Bharti, J. E. Nally, J. N. Ricaldi, M. A. Matthias, M. M Diaz , M. A Lovett and et al, "Leptospirosis: a zoonotic disease of global importance," Lancet Infect Dis, vol. 3, pp. 757-771, 2003.
[2] P. N. Levett. "Leptospirosis," Clin Microbiol Rev, vol. 14, pp. 296-326, 2001.
[3] J. Hot, S. Davis and H. Leirs, "A model of Leptospirosis infection in an African rodent to determine risk to humans : Seasonal fluctuations and the impact of rodent control," Acta Tropica, vol. 99, pp. 218-225, 2006.
[4] W. Triampo, D. Baowan, I. M. Tang, N. Nuttavet, J. Wong Ekkabut and G. Doungchawee, " A simple deterministic model for the spread of Leptospirosis in Thailand," International Journal of Biomedical Science, vol. 2, pp. 1306-1316, 2007.
[5] Division of Epidemiology, Annual Epidemiological Survillance Report, Ministry of Public Health, Thailand, 1997.
[6] Division of Epidemiology, Annual Epidemiological Survillance Report, Ministry of Public Health, Thailand, 1998.
[7] Division of Epidemiology, Annual Epidemiological Survillance Report, Ministry of Public Health, Thailand, 1999.
[8] Division of Epidemiology, Annual Epidemiological Survillance Report, Ministry of Public Health, Thailand, 2000.
[9] Division of Epidemiology, Annual Epidemiological Survillance Report, Ministry of Public Health, Thailand, 2001.
[10] Division of Epidemiology, Annual Epidemiological Survillance Report, Ministry of Public Health, Thailand, 2002.
[11] Division of Epidemiology, Annual Epidemiological Survillance Report, Ministry of Public Health, Thailand, 2003.
[12] Division of Epidemiology, Annual Epidemiological Survillance Report, Ministry of Public Health, Thailand, 2004.
[13] Division of Epidemiology, Annual Epidemiological Survillance Report, Ministry of Public Health, Thailand, 2005.
[14] Division of Epidemiology, Annual Epidemiological Survillance Report, Ministry of Public Health, Thailand, 2006.
[15] Division of Epidemiology, Annual Epidemiological Survillance Report, Ministry of Public Health, Thailand, 2007.
[16] Division of Epidemiology, Annual Epidemiological Survillance Report, Ministry of Public Health, Thailand, 2008.
[17] Division of Epidemiology, Annual Epidemiological Survillance Report, Ministry of Public Health, Thailand, 2009.
[18] Division of Epidemiology, Annual Epidemiological Survillance Report, Ministry of Public Health, Thailand, 2010.